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Angina

Angina is a specific type of chest discomfort caused by inadequate blood flow through the blood vessels (coronary vessels) of the heart muscle (myocardium). Angina affects approximately 3% to 5% of the population in the U.S. The most common cause is coronary artery disease (CAD) In CAD, blockages in the coronary arteries, called plaques, prevent an adequate amount of blood from reaching the heart muscle. Situations that require increased blood flow to the heart may cause angina in people with CAD. These include exercise, heavy meals, and stress.

There are two types of angina: stable and unstable. Stable angina is a pain or discomfort in the chest or adjacent areas caused by insufficient blood flow to the heart muscle. This chest pain is relieved by rest or medication within a short period of time, usually 15 minutes. Chest pain of a longer duration or pain appearing with a lower level of effort than before, even at rest, should be considered unstable angina. Unstable angina describes a syndrome that is intermediate between stable angina and myocardial infarction: an accelerating or "crescendo" pattern of chest pain that lasts longer than stable angina, occurs with less exertion or at rest, or is less responsive to medication.

Unstable angina and myocardial infarction are considered acute coronary syndromes, while stable angina is a chronic condition. Unstable angina occurs in approximately 6 out of every 10,000 people. Coronary artery disease due to atherosclerosis is by far the most common cause of unstable angina. The risk factors for CAD (which in turn causes angina) include the following:

  • Male Gender
  • Cigarette smoking
  • High cholesterol levels (in particular, high LDL and low HDL cholesterol)
  • High blood pressure (hypertension)
  • Diabetes
  • Family history of coronary heart disease before age 55
  • Sedentary lifestyle
  • Obesity

Symptoms include feeling of tightness, heavy pressure, or squeezing or crushing chest pain that:

  • is mid-sternal (under the breastbone) or slightly to the left
  • is not clearly localized
  • may radiate to shoulder, arm, jaw, neck, back, or other areas
  • may feel similar to gas or indigestion
  • is precipitated by activity, stress, or exertion
  • lasts 1 to 15 minutes
  • is usually relieved by rest and/or nitroglycerin

Your health care provider may note changes in your blood pressure. A heart murmur or arrhythmias (irregular heartbeats) may occur. An exercise tolerance test (stress test or treadmill test) may show ECG changes associated with the chest pain, which confirm the diagnosis of coronary artery disease in patients with angina.

A stress echocardiogram may show that the heart's ability to squeeze (contract) is altered. In some circumstances, your health care provider may request a heart scan or a coronary angiography to help assess the condition.

Some patients may need revascularization procedures to treat the underlying coronary artery disease. Revascularization procedures include PTCA (balloon angioplasty to a coronary artery) and surgery such as CABG (coronary artery bypass grafting).